Kratom was first found in 1907 by D. Hooper. This process is repeated in 1921. I. Field, which gave it the name of the alkaloid. For the first time Kratom tree structure was completely defined in 1964 by D. Zacarias, R. Rosenstein and J. Jeffrey.
Structurally similar to the alkaloid yohimbe alkaloids and voakanginom. Its relationship with other psychedelic substances on the basis of tryptamine, such as LSD or psilocybin, is less pronounced. Chemically, mitragynine called 9-methoxy-korinanteidin. Its molecular formula – C23H30N2O4, and a molecular weight – 398.5. Basic mitragynine looks like a non-crystalline white powder, melting at 102-106 degrees and boiling at 230-240 degrees. It is soluble in alcohol, chloroform and acetic acid. Hydrochloride salt dissolves at 243 degrees.
The traditional use in Thailand goes back in time, and its beginning can not be determined. The first reference to Kratom in Western literature belonged to Lowe, who in 1836 wrote that Malaysians used the plant as a substitute for opium when the latter was unavailable or too expensive.
In some areas of Thailand believed that parents will be given their daughters to those who use Kratom rather than those who use marijuana. Argued that those who use Kratom, hard-working, and those who use marijuana lazy. This view is supported by many people who report that they began to use the plant because of the desire to work more efficiently; they argue several Kratom health benefits, and also said that Kratom generates a steady desire to work.
The leaves are crushed, eaten fresh or dried form, make the various settings. From the leaves make the tea, add also in alcoholic drinks, their smoke. Leaves Kratom can be extracted, and from young shoots resin obtained by extraction. Resin prepared by repeated digestion Kratom leaves in water, then the resulting thick rolled into balls that are stored for a long time. Perhaps the most popular method in the world of cooking and consumption of Kratom.
While some people, primarily in Thailand have become dependent on Kratom, the plant does not produce addiction, if wisely used addiction is only possible when Kratom is used in doses high enough to cross over mu-receptors.
In 1895, EM Holmes identified Kratom as a mitragyna speciosa, and again pointed to its use as a substitute for opium. In 1907, L. Wray described methods of application such as smoking, chewing and tea. Hoping that the active chemical can be opened and examined for medical use, Wray had sent to Edinburgh University Kratom leaves and related plant – mitragyna parvifolia; from these samples Field singled mitragynine and mitraversin of parvifolia. In 1930 IH Burkill wrote that Kratom was also used as a poultice for wounds and as a remedy for fever.